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Allen Human Brain Atlas

The Allen Human Brain Atlas is a unique multi-modal atlas of the human brain, integrating anatomic and genomic information and coupled with a suite of visualization and data mining tools.

Key features:

  • Microarray data providing an "all genes, all structures" survey in multiple adult control brains
    • Genome-wide coverage - over 62,000 gene probes per expression profile
    • Comprehensive anatomic coverage - approximately 500 samples per hemisphere across cerebral, cerebellar and brainstem structures
    • Mapped with histology into unified 3-D anatomic framework based on MRI
    • Anatomic and gene-based search with options for comparing among structures or donors
    • Heat map and other viewing options, as well as files available for download
  • In situ hybridization image data comprising multiple data sets from targeted studies covering selected genes in specific brain regions
    • Subcortex study examining 55 genes across subcortical regions and 10 additional genes in hypothalamus in one male and one female donor
    • Cortex Study surveying 1,000 genes in visual and temporal cortex in multiple adult control brains
    • Schizophrenia Study of 60 genes in dorsolateral prefrontal cortex of over 50 control and schizophrenia cases
  • MRI data for brains used for all microarray and some ISH analyses
    • Multi-planar viewer for structural MRI
    • T1, T2 and DTI files for download
  • Brain Explorer® 3-D viewer for interactive viewing of brain anatomy and gene expression distribution, including inflated cortical surface views